JURISDICTIONAL TRANSPLANT PLATFORM
Every Organ. Every Patient. Every Second.
Afflo is the end-to-end transplant management platform that connects donor workflows, waitlist management, organ matching, offer decisions, and post-transplant outcomes into one real-time system — purpose-built for the complexity of transplantation.
Why It Matters: The Problem Afflo Solves
Transplantation Is Complex and Time-Critical
Every organ offer involves dozens of variables, multiple organizations, strict time windows, and a patient whose life depends on the outcome. The platforms transplant teams rely on need to match that complexity — and most don’t.
1 in 5
Recovered organs are not transplanted
Over 100,000 patients are on active waitlists in the US at any given time, and thousands of viable organs go unused each year. The gap between supply and demand makes every decision — and every platform — count.
5 hrs
Average time to process a single referral packet manually
Before a decision can even be made, teams must reconstruct clinical data from fragmented sources — a coordination problem disguised as a workflow.
24/7
Organ offers arrive around the clock, without warning
Deceased-donor decisions happen at any hour under extreme time pressure. Surgeons need the right data immediately.
WHAT AFFLO IS
The Operational Core of Your Transplant System
Afflo is the central platform where your transplant program runs — where referrals are received, patients are managed, organs are matched, logistics are coordinated, devices are deployed, and outcomes are tracked.
Because Afflo sits at the center of your operations, it captures real-time, end-to-end transactional data that no other system has. That data is what makes clinical AI meaningful. That data is what makes your performance reports accurate. That data is what connects your team, your partners, and your patients.
WHAT MAKES AFFLO DIFFERENT
| Real-time data
Every clinical event is captured as it happens — not batched, not exported, not lagged.
| Purpose-built
Designed from the ground up for transplantation, not adapted from a generic hospital system.
| Configurable
Policy rules, allocation logic, and workflows adapt to your jurisdiction without custom code.
| Open platform
Connect Afflo’s AI modules or plug in your transplant centre’s own research models.
| Modular adoption
Start with one workflow. Expand as you’re ready. No rip-and-replace required.
From targeted modules to a full system deployment, Afflo integrates seamlessly into your program — without requiring you to adapt your operations.
The Transplant Lifecycle
A Truly End-to-End Transplant Platform
Afflo connects every stage of the transplant journey into one continuous system. Each stage is powerful on its own — and exponentially stronger when they work together.
Donor Management
Referral capture, deceased & living donor workflows, real-time status
Waitlist & Intake
Referral intake, AI document processing, eligibility & waitlist management
Matching & Allocation
Policy-driven matching engine, HLA/VXM, equity- aligned offer ranking
Offer & Decision
Offer screening, AI-assisted evaluation, hospital-based rules exclusion, local policy
Logistics and Device Coordination
Transport orchestration, device deployment, real-time tracking
Who We Serve
Built for Every Layer of Transplantation
TRANSPLANT NETWORKS
Jurisdiction-wide allocation at scale
National and regional networks need policy governance, real-time matching, and equity-aligned allocation across every centre. Afflo is the only platform built for this layer of transplantation.
TRANSPLANT PROGRAMS
From first referral to last follow-up
Transplant centres need connected, configurable workflows that reduce coordinator burden and support faster, more confident clinical decisions. Afflo covers the full patient journey.
DONOR ORGANIZATIONS
Fewer missed donations. Less waste.
OPOs and donor organizations need seamless referral capture, interoperability with hospital systems, and real-time coordination with transplant centres. Afflo connects every stakeholder
Platform Capabilities
From automated intake to post-transplant outcomes, Afflo’s capabilities are embedded in the workflows your teams already use — not bolted on as separate tools.
Intelligent Document & Referral Intake
Afflo automatically ingests referral packets — faxes, PDFs, scanned forms — and extracts key clinical, demographic, and immunologic data into structured records. Coordinators review and validate rather than transcribe, cutting intake time and error rates significantly.
Waitlist Intelligence & Risk Monitoring
Afflo continuously tracks every patient — testing intervals, expiring workups, psychosocial requirements, eligibility status — and generates targeted alerts before problems occur. Coordinators spend less time chasing and more time caring.
Policy-Driven Matching & Allocation
Afflo’s configurable matching engine applies your jurisdiction’s full clinical, operational, and policy logic to rank candidates and generate offers. Virtual crossmatch at allele, alpha-beta, and epitope/eplet resolution improves match quality and expands access for sensitized patients.
Policy Simulation & Governance
Before any allocation rule goes live, Afflo lets policy teams run it against historical data to model impact on utilization, equity, and outcomes. The Policy Management Workbench makes policy iteration fast, auditable, and safe.
Organ Offer Decision Support
When an offer arrives, Afflo’s AI surfaces donor–recipient compatibility, predicted graft survival, and estimated time to the next comparable offer — giving surgeons the quantitative context they need to make faster, more consistent decisions around the clock.
Performance Insights & Analytics
Afflo’s data warehouse turns real-time operational data into dashboards that surface utilization patterns, equity metrics, offer outcomes, and coordinator workload. No data export required — the insight lives where the work happens.
OPEN PLATFORM
YOUR MODELS. OUR DATA. BETTER OUTCOMES.
Afflo is designed to be the integration platform for AI in transplant — not just the provider of it. Because Afflo sits at the operational core, it holds the real-time, end-to-end transactional data that AI models need to be clinically meaningful. Connect Afflo’s own validated models or bring your transplant centre’s research models and run them against live data, inside the workflows where decisions are actually made.
What Afflo Provides
→ Real-time transactional data across the full transplant lifecycle
→ Secure inference API framework for plugging in external AI models
→ Configurable UI panels to surface model outputs within live workflows
→ Audit-ready logging of every AI- assisted decision
→ Data warehouse for model training, validation, and historical simulation
What Your Team Brings
→ Institution-specific models trained on your patient populations
→ Research models from academic or clinical partnerships
→ Jurisdiction-specific allocation optimization algorithms
→ Specialty organ models adapted to local practice patterns
→ Published research models ready for clinical deployment
The data problem in transplant AI is not a shortage of researchers or algorithms — it is a shortage of real-time, end-to-end operational data. Afflo solves that problem. When your model runs inside Afflo, it runs on the most complete, most current transplant data available.
Why Transplant Programs Choose Afflo
Purpose-Built for Transplant
Every workflow, every data model, every feature was designed around the actual realities of transplant — not adapted from a generic hospital system.
Modular Adoption
Start with one module — waitlist management, referral intake, or offer analytics — and expand as you’re ready. No big-bang implementation required.
Real-Time at Its Core
Afflo captures clinical events as they happen. That currency is what makes AI predictions clinically meaningful and performance reports accurate.
HIPAA & ISO 27001
Enterprise-grade security is built into the platform architecture, not bolted on. Your data is protected at every layer.
Configurable, Not Customized
Allocation rules, policy logic, and workflows are configured to your jurisdiction without custom code — which means faster implementation and lower long-term cost.
Phased, Low-Risk Implementation
Afflo integrates with your EMRs, lab systems, registries, and legacy platforms. Your team continues operating while capabilities are added.
Discover What’s Possible with Afflo
Ready to modernize your transplant system? Let's talk.